| 세션명 | Virtual Lightning Talk Session |
|---|---|
| 발표장 | 온라인 |
| 논문코드 | VLT-46 |
| 발표일 | --2023 |
| 발표시간 | 2024-04-03~04-07 |
| 논문제목 | Adipocytolysis induced by fatty acid-modified gas-generating polymer |
| 발표자 | 이인영 |
| 발표자 소속 | 한양대학교 |
| 저자 | 이인영, 이혜원, 이근용† |
| 소속 | 한양대학교 |
| 논문초록 | In the treatment of obesity, nanoparticles have emerged as promising strategies for non-surgical esthetic procedures aimed at body contouring. Especially functionalized polymeric nanoparticles have shown potential to overcome challenges associated with conventional treatments, such as organ toxicity and vascular damage. We hypothesize in this study that polymer nanoparticles modified with fatty acids and capable of releasing CO2, could be useful for localized fat reduction by utilizing the active fatty acid metabolism of adipocytes. Fatty acid-modified poly(lactic-co-glycolic acid) nanoparticles incapsulating calcium carbonate were prepared as gas-generating nanoparticulate systems, which have shown efficacy in reducing local fat in vivo. This approach may be beneficial to developing polymer nanoparticulate systems for treatment of various diseases, highlighting their versatility and therapeutic potential. |
THE POLYMER SOCIETY OF KOREA